Pentobarbital will decrease the level or effect of doravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. pentobarbital will decrease the level or effect of conjugated estrogens, vaginal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will decrease the level or effect of tinidazole by affecting hepatic/intestinal enzyme CYP3A4... https://socialbaskets.com/story5930218/fascination-circa-pentobarbital-effects