The pronunciation of "use" can adjust according to whether it's made use of to be a verb or simply a noun. In both of those situations, it commences having a 'y' sound, as in "Of course." This is certainly followed by the 'u' audio, similar to the 'u' in https://captainbookmark.com/story20266693/what-does-how-to-use-conolidine-mean